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again, Most synthetic cannabinoids are agonists of the cannabinoid receptors. They have been design to be similar to THC the natural cannabinoid with the strongest binding affinity to the CB1 receptor, which is link to the psychoactive effects or “high” of marijuana. These synthetic analogs often have greater binding affinity and greater potency to the CB1 receptors. There are several synthetic cannabinoid families classified based on the base structure
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more so, Reported user negative effects include palpitations, paranoia, intense anxiety, nausea, vomiting, confusion, poor coordination, and seizures. There have also been reports of a strong compulsion to re-dose, withdrawal symptoms, and persistent cravings. There have been several deaths link to synthetic cannabinoids
in addition, The Centers for Disease Control and Prevention (CDC) found that the number of deaths from synthetic cannabinoid use triple between 2014 and 2015. the United States Food and Drug Administration warned of significant health risks from synthetic cannabinoid products that contain the rat poison brodifacoum, which is add because it is thought to extend the duration of the drugs’ effects. Severe illnesses and death have result from this contamination. Buy Black mamba K2 spray online.